I've never done Buoy 10, but as far as estuaries go -- depends how many rods you have. Lots of people will run a herring/anchovie rig on one rod (with or without flasher/dodger), and one spinner rod, and swap them all out to whichever gets hit (and as Irishrover mentioned, learning to rig a helmet will make you a happier and more effective fisherman, and even reduces the bait bill -- win/win). If you have 3 rods or more, maybe even run a plug on one (Maglip 4.5 can be flatlined, a K11-15 can be fished with a diver), or one flasher, one without. Had recent success with a Toman spinner. Ran about a 1.5 foot sliding dropper to an 8oz (I think), but weight always depends on depth and current, then about the same/slightly longer leader to a (Shortbus) flasher, then about 3-4 feet to the spinner. When you get a hit, or see a zillion fish jumping, keep trolling back through the area. Drop the rig in (without tangling it) until you feel it hot bottom, then reel up about a foot (watch the depth finder and adjust depth accordingly). Keep the angle of your line at 45 degrees or less. Don't sweat the uphill/downhill thing too much (but go the way that keeps your neighbors happy) Be patient. Slack tides are your friend.
That's about all I got.